![]() However, a certain level of stomach acid is needed not only for digesting food but for killing potentially harmful microbes (including bacteria and fungi) before they reach the intestines. They work by inhibiting certain stomach cells from “pumping” acid into the stomach. Proton pump inhibitors (PPIs) are medications commonly prescribed for acid reflux. You’ve used proton pump inhibitors (PPIs). This includes very young children, the elderly, and people taking immunosuppressant drugs like steroids, such as patients with certain autoimmune diseases and cancers. Overgrowth of fungi is often more common in people with weakened immune systems, research has shown. Steinberg, these are some of the most common: You’re immunocompromised. ![]() So, what are the major factors? According to Dr. While SIFO may be causing your GI symptoms, there are deeper root causes that lead to unhealthy proliferation of fungi in the first place. “If there is fungal overgrowth in other places, it makes me think there may be fungal overgrowth in your gut as well,” she says. Steinberg and others at Parsley Health to investigate further. While these non-GI symptoms aren’t always present in people with SIFO, they do prompt Dr. Toenail fungus, anal itching, and thrush (a white coating on the tongue) may also be indicators that you have some sort of systemic fungal overgrowth occurring. Some patients also experience itching behind the ears.” “But my red flags for SIFO go up when I see other signs of fungal overgrowth such as chronic yeast infections or rashes in areas where skin meets skin, like armpits or under the breasts. ![]() “The most common symptoms of SIFO are really the same as those for SIBO ,” says Dr. In one study, around 25 percent of people with unexplained GI issues were found to have SIFO, and their most common symptoms were belching, bloating, indigestion, nausea, diarrhea, and gas. ( Candida overgrowth can take place in other areas of the body, too-learn how it can affect the health of your skin and nails, vagina, mood, and more.) What are common SIFO symptoms? A variety of factors, from lack of movement to low stomach acid to certain medications, may contribute to fungal overgrowth in the gut. “But, like anything else in the gut, when gets really out of balance, that’s when it becomes an issue,” says Dr. In fact, Candida normally lives on the skin and inside the body, in places like the mouth, throat, gut, and vagina, without causing problems. Candida is a member of the fungal family, but is typically referred to as a yeast, and it’s actually supposed to be in your gut. Research has found that 97 percent of the fungi associated with SIFO is some form of Candida, such as Candida albicans. “SIFO is essentially fungal overgrowth in the small bowel (or small intestines), as opposed to the bacterial overgrowth that occurs in SIBO ,” says Sarah Steinberg, MDPhD, a double-board certified internal medicine and gastroenterology physician at Parsley Health. Keep reading to get the rundown on SIFO, which could be the underlying cause of your GI symptoms. Often, it can get mixed up with SIBO (small intestinal bacterial overgrowth), but there are key differences and they don’t necessarily respond to the same treatments. SIFO stands for small intestinal fungal overgrowth-and it’s responsible for a range of seriously unpleasant gastrointestinal symptoms like bloating, abdominal pain, and diarrhea.
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